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Invitrogen
KDM2A Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-115458
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human KDM2A(Accession Q9Y2K7), corresponding to amino acid residues N372-A422.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total KDM2A.
Target Information
FBXL11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box). The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXL11 belongs to the Fbls class and, in addition to an F-box, contains at least 6 highly degenerated leucine-rich repeats.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: [Histone-H3]-lysine-36 demethylase 1A; CXXC-type zinc finger protein 8; DKFZp434M1735; F-box and leucine-rich repeat protein 11; F-box protein containing leucine repeats; F-box/LRR-repeat protein 11; FLJ00115; FLJ46431; jmjC domain-containing histone demethylation protein 1A; jumonji C domain-containing histone demethylase 1A; KDM2A-C620; KDM2A-delta N; KDM2A-N782; lysine (K)-specific demethylase 2A; SF-KDM2A; unnamed protein product
Gene Aliases: 100043628; 5530401A10Rik; CXXC8; FBL11; FBL7; FBXL11; Gm4560; Jhdm1; JHDM1A; lalina; LILINA
UniProt ID: (Human) Q9Y2K7, (Mouse) P59997
Entrez Gene ID: (Human) 22992, (Mouse) 225876
negative regulation of transcription from RNA polymerase II promoter
in utero embryonic development
neural tube closure
heart looping
double-strand break repair via nonhomologous end joining
chromatin remodeling
regulation of transcription from RNA polymerase II promoter
positive regulation of gene expression
negative regulation of gene expression
neuron differentiation
circadian regulation of gene expression
multicellular organism growth
regulation of circadian rhythm
negative regulation of apoptotic process
positive regulation of gene expression, epigenetic
embryonic organ morphogenesis
neuroepithelial cell differentiation
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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