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Invitrogen
KHDC1 Polyclonal Antibody
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产品信息
PA5-112972
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human KH homology domain-containing protein 1 protein (74-237AA)
偶联物
形式
Liquid
浓度
2.5 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
KHDC1 family members are K-homology (KH) domain-containing RNA binding proteins that are involved in various aspects of RNA metabolism, ranging from transcription to RNA splicing, transportation, translation, and stability. KHDC1 is highly expressed in oocytes and interacts with cytoplasmic polyadenylation element-binding protein 1 (CPEB1), a key translational regulator controlling the polyA length of mRNAs. KHDC1 functions as a global translational repressor and induces apoptosis through an ER-dependent signaling pathway and that the C-terminal putative trans-membrane motif (TMM) is critical for its activities.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: KH homology domain containing 1A; KH homology domain-containing protein 1; KH homology domain-containing protein 1A; MGC10818; Nur77 downstream gene 1 protein; Nur77 downstream protein 1
基因别名: AU014713; bA257K9.4; C6orf147; C6orf148; C88118; Em:AC019205.8; KHDC1; Khdc1a; NDG1
UniProt ID: (Human) Q4VXA5, (Mouse) Q3UWR2
Entrez Gene ID: (Human) 80759, (Mouse) 368204
