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MA5-15649 targets KLHL12 in indirect ELISA, WB applications and shows reactivity with Human samples.
The MA5-15649 immunogen is purified recombinant fragment of human KLHL12 expressed in E. Coli.
MA5-15649 detects KLHL12 which has a predicted molecular weight of approximately 63kDa.
Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CUL3-interacting protein 1; DKIR homolog; FLJ27152; hDKIR; kelch-like family member 12; Kelch-like protein 12; kelch-like protein C3IP1
基因别名: C3IP1; DKIR; KLHL12
UniProt ID: (Human) Q53G59
Entrez Gene ID: (Human) 59349