Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Abnova
KSR2 Polyclonal Antibody, MaxPab™
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 1
KSR2 Antibody (H00283455-B01P) in WB
Western Blot analysis of KSR2 expression in transfected 293T cell line (H00283455-T01) by KSR2 MaxPab polyclonal antibody.
Lane 1: KSR2 transfected lysate(91.19 KDa).
Lane 2: Non-transfected lysate.
Lane 1: KSR2 transfected lysate(91.19 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00283455-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KSR2 (NP_775869.2, 1 a.a. approximately 829 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MTDEQVCETV EKYGANREEC ARLNASLSCL RNVHMSGGNL SKQDWTIQWP TTETGKENNP VCPPEPTPWI RTHLSQSPRV PSKCVQHYCH TSPTPGAPVY THVDRLTVDA YPGLCPPPPL ESGHRSLPPS PRQRHAVRTP PRTPNIVTTV TPPGTPPMRK KNKLKPPGTP PPSSRKLIHL IPGFTALHRS KSHEFQLGHR VDEAHTPKAK KKSKPLNLKI HSSVGSCENI PSQQRSPLLS ERSLRSFFVG HAPFLPSTPP VHTEANFSAN TLSVPRWSPQ IPRRDLGNSI KHRFSTKYWM SQTCTVCGKG MLFGLKCKNC KLKCHNKCTK EAPPCHLLII HRGDPARLVR TESVPCDINN PLRKPPRYSD LHISQTLPKT NKINKDHIPV PYQPDSSSNP SSTTSSTPSS PAPPLPPSAT PPSPLHPSPQ CTRQQKNFNL PASHYYKYKQ QFIFPDVVPV PETPTRAPQV ILHPVTSNPI LEGNPLLQIE VEPTSENEEV HDEAEESEDD FEEMNLSLLS ARSFPRKASQ TSIFLQEWDI PFEQLEIGEL IGKGRFGQVY HGRWHGEVAI RLIDIERDNE DQLKAFKREV MAYRQTRHEN VVLFMGACMS PPHLAIITSL CKGRTLYSVV RDAKIVLDVN KTRQIAQEIV KGMGYLHAKG ILHKDLKSKN VFYDNGKVVI TDFGLFSISG VLQAGRREDK LRIQNGWLCH LAPEIIRQLS PDTEEDKLPF SKHSDVFALG TIWYELHARE WPFKTQPAEA IIWQMGTGMK PNLSQIGMGK EISDILLFCW AFEQEERPTF TKLMDMLEKL PKRNRRLSHP GHFWKSAEL
靶标信息
KSR2 serine/threonine kinase or kinase suppressor of Ras 2 specifically regulates the activity of MEKK3 and COT but not other members of the MAP3K family. KSR interacts with a regulatory Raf molecule in cis to induce a conformational switch of MEK, facilitating MEK's phosphorylation by a separate catalytic Raf molecule in trans. Blocks MAP3K8 kinase activity and MAP3K8- mediated signaling. Acts as a negative regulator of MAP3K3- mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: hKSR2; Kinase suppressor of Ras 2
基因别名: KSR2
UniProt ID: (Human) Q6VAB6
Entrez Gene ID: (Human) 283455
