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Invitrogen
LAPTM4B Polyclonal Antibody
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LAPTM4B Antibody (PA5-100153) in ICC/IF
Immunofluorescent analysis of LAPTM4B in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and LAPTM4B polyclonal antibody (Product # PA5-100153) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
产品信息
PA5-100153
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human LAPTM4B(Accession Q86VI4), corresponding to amino acid residues A81-L131.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total LAPTM4B.
靶标信息
LAPTM4B is a multi-pass membrane protein. It belongs to the LAPTM4/LAPTM5 transporter family. LAPTM4b has active role in disease progression of malignant cells and is involved in cell proliferation and multidrug resistance. The genetic polymorphism of LAPTM4B is a potential risk factor for the development of colon cancer and gastric cancer. The research results also indicated that LAPTM4B may be a clinically useful prognostic indicator for ovarian carcinoma and may play a role in human hepatocellular carcinoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: lysosomal associated protein transmembrane 4 beta; lysosomal-associated protein transmembrane 4B; lysosomal-associated transmembrane protein 4; Lysosomal-associated transmembrane protein 4B; Lysosome-associated transmembrane protein 4-beta
基因别名: C330023P13Rik; LAPTM4B; LAPTM4beta; LC27; PSEC0001
UniProt ID: (Human) Q86VI4, (Rat) Q5U1W4, (Mouse) Q91XQ6
Entrez Gene ID: (Human) 55353, (Rat) 315047, (Mouse) 114128
