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Invitrogen
LAPTM5 Polyclonal Antibody
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LAPTM5 Antibody (PA5-23585) in IHC (P)
Immunohistochemistry analysis of LAPTM5 in formalin fixed and paraffin embedded human lymph node. Samples were incubated with LAPTM5 polyclonal antibody (Product # PA5-23585) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-23585
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 23-49 amino acids from the N-terminal region of human LAPTM5
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
200 µg
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with bovine based on sequence homology.
靶标信息
This gene encodes a transmembrane receptor that is associated with lysosomes. The encoded protein, also known as E3 protein, may play a role in hematopoiesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CD40-ligand-activated specific transcripts; human retinoic acid-inducible E3 protein; KIAA0085; lysosomal associated multispanning membrane protein 5; lysosomal multispanning membrane protein 5; lysosomal-associated multitransmembrane protein 5; retinoic acid-inducible E3 protein; unnamed protein product
基因别名: CLAST6
UniProt ID: (Human) Q13571
Entrez Gene ID: (Human) 7805
defense response to tumor cell
positive regulation of cytokine production involved in immune response
protein targeting to lysosome
intracellular protein transport
induction of programmed cell death
positive regulation of protein ubiquitination
negative regulation of interferon-gamma production
negative regulation of interleukin-2 production
positive regulation of interleukin-12 production
positive regulation of interleukin-6 production
positive regulation of MAPK cascade
negative regulation of activated T cell proliferation
negative regulation of T cell receptor signaling pathway
negative regulation of T cell activation
negative regulation of B cell activation
positive regulation of macrophage cytokine production
Golgi to lysosome transport
intrinsic apoptotic signaling pathway
regulation of lysosomal membrane permeability
positive regulation of lysosomal membrane permeability
negative regulation of pre-B cell receptor expression
positive regulation of NIK/NF-kappaB signaling
positive regulation of tumor necrosis factor-mediated signaling pathway
negative regulation of autophagic cell death
positive regulation of lysosomal protein catabolic process
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
positive regulation of receptor catabolic process
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