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Invitrogen
LILRB5 Polyclonal Antibody
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LILRB5 Antibody (PA5-47442) in WB
Western blot analysis of LILRB5 lysates of Human bone marrow. PVDF membrane was probed with 0.5 µg/mL LILRB5 Polyclonal Antibody (Product # PA5-47442) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody. A specific band was detected for LILRB5/CD85c/LIR-8 at approximately 64 kDa (as indicated). This experiment was conducted under reducing conditions.
产品信息
PA5-47442
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant human LILRB5/CD85c/LIR-8 Arg18-His456
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In direct ELISAs, approximately 20% cross-reactivity with recombinant human (rh) LIR-4/ILT6 is observed, and approximately 10% cross-reactivity with rhILT5, rhLIR-5/ILT3, rhLIR-6, and rhLILRA5 is observed, and less than 5% cross-reactivity with rhILT2, rhILT4, and rhLIR-7 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
This gene is a member of the leukocyte immunoglobulin-likereceptor (LIR) family, which is found in a gene cluster atchromosomal region 19q13.4. The encoded protein belongs to thesubfamily B class of LIR receptors which contain two or fourextracellular immunoglobulin domains, a transmembrane domain, andtwo to four cytoplasmic immunoreceptor tyrosine-based inhibitorymotifs (ITIMs). Several other LIR subfamily B receptors areexpressed on immune cells where they bind to MHC class I moleculeson antigen-presenting cells and inhibit stimulation of an immuneresponse. Multiple transcript variants encoding different isoformshave been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD85 antigen-like family member C; CD85c; leucocyte Ig-like receptor B5; Leukocyte immunoglobulin-like receptor 8; Leukocyte immunoglobulin-like receptor subfamily B member 5; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5; LIR-8
基因别名: CD85C; LILRB5; LIR-8; LIR8
UniProt ID: (Human) O75023
Entrez Gene ID: (Human) 10990
