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Invitrogen
LITAF Polyclonal Antibody
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产品信息
PA5-52367
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: APPSYEETVA VNSYYPTPPA PMPGPTTGLV TGPDGKGMNP PSYYTQPAPI PNNNPITVQT VYVQHPITFL DRPIQMCCPS CNKMIVSQLS YNAGALTWLS CGSLCLLGCI AGCCFIPFCV DALQDVDHYC PNC
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 89%.
靶标信息
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CMT1C; FLJ38636; lipopolysaccharide-induced TNF factor; lipopolysaccharide-induced TNF-alpha factor; Lipopolysaccharide-induced tumor necrosis factor-alpha factor; LPS-induced TNF-alpha factor; MGC116698; MGC116700; MGC116701; MGC125274; MGC125275; MGC125276; p53-induced gene 7 protein; PIG 7; Small integral membrane protein of lysosome/late endosome; tumor protein p53 inducible protein 7
基因别名: LITAF; PIG7; SIMPLE; TP53I7
UniProt ID: (Human) Q99732
Entrez Gene ID: (Human) 9516
regulation of cytokine production
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
apoptotic process
signal transduction
aging
negative regulation of NF-kappaB import into nucleus
positive regulation of I-kappaB kinase/NF-kappaB signaling
cellular response to lipopolysaccharide
