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Rockland
LRFN4 Polyclonal Antibody
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LRFN4 Antibody (600-401-CM3) in ICC/IF
Immunofluorescence Microscopy of LRFN4 antibody. Tissue: mouse brain tissue. Fixation: 0.5% PFA. Antigen retrieval: not required. Primary antibody: LRFN4 antibody at 20 µg/mL for 1 hr at RT. Secondary antibody: Fluorescein rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: LRFN4 is a single pass membrane protein. Staining: LRFN4 as red fluorescent signal.
产品信息
600-401-CM3
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Anti-LRFN4 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14amino acid synthetic peptide near the C-terminus of human LRFN4.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
LRFN4 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN4 are known to exist.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: fibronectin type III, immunoglobulin and leucine rich repeat domains 6; Leucine-rich repeat and fibronectin type-III domain-containing protein 4; synaptic adhesion-like molecule 3
基因别名: BC023156; FIGLER6; LRFN4; SALM3; SALM3.
UniProt ID: (Human) Q6PJG9, (Rat) D4ABX8, (Mouse) Q80XU8
Entrez Gene ID: (Human) 78999, (Rat) 688721, (Mouse) 225875
