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Invitrogen
LRRC17 Polyclonal Antibody
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产品信息
PA5-113953
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the middle region of human LRRC17
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: YVFPIQTLDC KRKELKKVPN NIPPDIVKLD LSYNKINQLR PKEFEDVHEL
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Cow: 93%; Dog: 100%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%
靶标信息
Leucine-rich repeat-containing protein 17 (LRRC17) is an LRR protein predominantly expressed by osteoblasts. LRRC17 acts as a negative regulator of receptor activator of NF-kappaB ligand (RANKL)-induced osteoclast differentiation. It has been reported that low plasma level of LRRC17 is an independent risk factor for osteoporotic fractures.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 37 kDa leucine-rich repeat (LRR) protein; Leucine-rich repeat-containing protein 17; p37NB
基因别名: LRRC17; P37NB; UNQ3076/PRO9909
UniProt ID: (Human) Q8N6Y2
Entrez Gene ID: (Human) 10234
