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Invitrogen
LRRC8B Polyclonal Antibody
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产品信息
PA5-53675
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: PSTSSRLEHF VAILHKCFDS PWTTRALSET VAEQSVRPLK LSKSKILLSS SGCSADIDSG KQSLPYPQPG LESAGIESPT SSVLDKKEGE QAKAIFEKVK RFRMHVEQKD
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.
靶标信息
Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: leucine rich repeat containing 8 family, member B; leucine-rich repeat containing 8 family member B; Leucine-rich repeat-containing protein 8B; T cell activation leucine repeat rich protein; T-cell activation leucine repeat-rich protein; TA-LRRP; Volume-regulated anion channel subunit LRRC8B
基因别名: KIAA0231; LRRC8B; TA-LRRP; TALRRP; UNQ6413/PRO21207
UniProt ID: (Human) Q6P9F7
Entrez Gene ID: (Human) 23507
