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Invitrogen
VCP Monoclonal Antibody (Hs-14), FITC
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA1-10384
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgM
Class
Monoclonal
Type
Antibody
Clone
Hs-14
Immunogen
Freshly ejaculated human sperms were washed in PBS and extracted in 3% acetic acid, 10% glycerol, 30 mM benzaminidine. The acid extract was dialyzed against 0.2% acetic acid and subsequently used for immunization.
Conjugate
FITC
FITC
FITC
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.06 mg/mL
Purification
Size-exclusion chromatography
Storage buffer
TBS, pH 8.0, with 0.2% BSA
Contains
15mM sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody reacts with VCP (valosin-containing protein) a 220 kDa intra-acrosomal protein.
Target Information
The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 15S Mg(2+)-ATPase p97 subunit; AAA ATPase p97; homolog of yeast cdc48; Inv protein; or HEL-S-70; p97 atpase; TER ATPase; Transitional endoplasmic reticulum ATPase; Valosin-containing protein; VCP
Gene Aliases: 3110001E05; CDC48; p97; p97/VCP; Vcp
UniProt ID: (Mouse) Q01853
Entrez Gene ID: (Mouse) 269523
nucleotide binding
receptor binding
protein binding
ATP binding
lipid binding
hydrolase activity
ATPase activity
protein phosphatase binding
protein domain specific binding
polyubiquitin binding
protein complex binding
deubiquitinase activator activity
identical protein binding
ADP binding
ubiquitin-like protein ligase binding
poly(A) RNA binding
ubiquitin-specific protease binding
DNA repair
double-strand break repair
ubiquitin-dependent protein catabolic process
transport
ER to Golgi vesicle-mediated transport
activation of cysteine-type endopeptidase activity involved in apoptotic process
cellular response to DNA damage stimulus
protein ubiquitination
protein N-linked glycosylation via asparagine
viral genome replication
translesion synthesis
ER-associated ubiquitin-dependent protein catabolic process
retrograde protein transport, ER to cytosol
positive regulation of protein complex assembly
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
protein hexamerization
positive regulation of protein catabolic process
protein homooligomerization
aggresome assembly
ER-associated misfolded protein catabolic process
positive regulation of protein K63-linked deubiquitination
positive regulation of Lys63-specific deubiquitinase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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