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Invitrogen
CD263 (TRAIL-R3) Recombinant Rabbit Monoclonal Antibody (003), PE
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CD263 (TRAIL-R3) Antibody (MA5-46672) in Flow
Flow cytometry analysis of TRAIL-R3 (CD263) in human whole blood granulocytes using CD263 (TRAIL-R3), PE Recombinant Monoclonal (Product # MA5-46672). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-46672
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
003
抗原
Recombinant protein ecoding Human CD263 (TRAIL-R3) (Met1-Pro235).
偶联物
PE
PE
PE
激发/发射光谱
565/576 nm
查看光谱
形式
Liquid
浓度
100 µg/mL
纯化类型
Protein A
保存液
PBS with 0.5% BSA
内含物
0.09% sodium azide
保存条件
4°C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Human TRAIL-R3 (CD263) (Met1-Pro235) and conjugated with PE under optimum conditions, the unreacted PE was removed.
Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
靶标信息
TRAIL-R3 (CD263) is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Antagonist decoy receptor for TRAIL/Apo-2L; CD263; DcR1; Decoy receptor 1; Decoy TRAIL receptor without death domain; Lymphocyte inhibitor of TRAIL; MGC149501; MGC149502; TNF-related apoptosis-inducing ligand receptor 3; TRAIL receptor 3; TRAIL receptor without an intracellular domain; Tumor necrosis factor receptor superfamily member 10C
基因别名: DCR1; LIT; TNFRSF10C; TRAILR3; TRID; UNQ321/PRO366
Entrez Gene ID: (Human) 8794
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