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Invitrogen
MAD4 Polyclonal Antibody
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MAD4 Antibody (PA5-109997) in WB
Western blot analysis of MAD4 in extracts of Mouse lung. Samples were incubated with MAD4 Polyclonal antibody (Product # PA5-109997) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
产品信息
PA5-109997
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 110-209 of human MXD4 (NP_006445.1).
偶联物
形式
Liquid
浓度
1.1 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: RRALSIKEQL QQEHRFLKRR LEQLSVQSVE RVRTDSTGSA VSTDDSEQEV DIEGMEFGPG ELDSVGSSSD ADDHYSLQSG TGGDSGFGPH CRRLGRPALS
靶标信息
This gene is a member of the MAD gene family. The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: max dimerization protein 4; max dimerizer 4; max-associated protein 4; max-interacting transcriptional repressor MAD4
基因别名: 2810410A03Rik; bHLHc12; Mad4
Entrez Gene ID: (Mouse) 17122
