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Invitrogen
MARCH2 Polyclonal Antibody
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产品信息
PA5-30620
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human MARCH2. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: HepG2 membrane.
Predicted reactivity: Mouse (94%), Rat (94%), Zebrafish (81%), Xenopus laevis (80%), Pig (95%), Bovine (91%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]; Nakamura et al., 2005 [PubMed 15689499]).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E3 ubiquitin-protein ligase MARCHF2; MARCH-II; membrane associated ring finger 2; membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase; Membrane-associated RING finger protein 2; Membrane-associated RING-CH protein II; RING finger protein 172; RING-type E3 ubiquitin transferase MARCHF2
基因别名: HSPC240; MARCH-II; MARCH2; MARCHF2; RNF172
UniProt ID: (Human) Q9P0N8
Entrez Gene ID: (Human) 51257
