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Invitrogen
MARCKSL1 Polyclonal Antibody
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产品信息
PA5-77147
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length Human MARCKSL1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
MARCKS (Myristoylated alanine-rich protein kinase C substrate), also designated 80K or 80K-L, is a 332 amino acid protein that localizes to the plasma membrane and functions as a major cellular substrate for protein kinase C (PKC). MARCKSL1 (MARCKS-like protein 1), also known as MacMARCKS, MLP, MRP, or F52, is a 195 amino acid protein that, like MARCKS, is a major substrate for PKC. Expressed in a variety of tissues with highest levels found in testis and uterus, MARCKSL1 participates in the coordination of membrane-cytoskeletal signaling events, including secretion, migration, phagocytosis and cell adhesion. Additionally, MARCKSL1 functions as a regulator of Integrin activation and is thought to regulate Integrin-dependent signal transduction pathways, especially those involved in macrophage spreading.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Brain protein F52; Mac-MARCKS; macMARCKS; Macrophage myristoylated alanine-rich C kinase substrate; MARCKS-like 1; MARCKS-like protein 1; MARCKS-related protein; myristoylated alanine-rich C kinase substrate
基因别名: AL022768; AW215397; AW536807; D4Bc1; F52; MACMARCKS; Macs2; Macs3; MARCKSL1; MLP; MLP1; MRP
UniProt ID: (Human) P49006, (Rat) Q9EPH2, (Mouse) P28667
Entrez Gene ID: (Human) 65108, (Rat) 81520, (Mouse) 17357
