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Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji.
Predicted reactivity: Mouse (90%), Rat (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DBL's big sister; FLJ12122; Guanine nucleotide exchange factor DBS; MCF2 transforming sequence-like protein; MCF2-transforming sequence-like protein; RP11-98F14.2
基因别名: ARHGEF14; DBS; KIAA0362; MCF2L; OST
UniProt ID: (Human) O15068
Entrez Gene ID: (Human) 23263