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Invitrogen
MCHR1 Polyclonal Antibody
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产品信息
PA5-32917
产品规格
种属反应
Bovine,
Dog,
Human,
Non-human primate
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 18 amino acid peptide from C-terminus of human MCHR1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Bovine, Dog, Panda (100%); Mouse, Rat, Horse, Pig (94%); Hamster, Elephant (89%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
靶标信息
MCHR1 is a member of the G protein-coupled receptor family 1. It is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G protein-coupled receptor 24; G-protein coupled receptor 24; GPCR24; MCH 1 receptor; MCH receptor 1; MCH-1R; MCH1; MCH1R; Melanin-concentrating hormone receptor 1; melanin-concentrating hormone receptor subtype 1; SLC-1; Somatostatin receptor-like protein
基因别名: GPR24; MCH-1R; MCH1R; MCHR1; SLC-1; SLC1
UniProt ID: (Human) Q99705
Entrez Gene ID: (Bovine) 540119, (Human) 2847, (Dog) 403563
generation of precursor metabolites and energy
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
feeding behavior
