Rockland

MD-1 Polyclonal Antibody

Name: MD-1 Polyclonal Antibody
Brand: Rockland
SKU: 600-401-CS2

查看其他14个MD-1抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (2)

MD-1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 2

MD-1 Antibody (600-401-CS2) in IHC (P)

Immunohistochemistry of MD-1 antibody. Tissue: human spleen tissue. Fixation: formalin fixed paraffin embedded. Antigen retrieval: not required. Primary antibody: MD-1 antibody at 2.5 µg/mL for 1 hr at RT. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: MD-1 is secreted. Staining: MD-1 is stained with hematoxylin purple nuclear counterstain.

Product Image Gallery

产品信息

600-401-CS2

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-2 µg/mL

免疫组化（石蜡） (IHC (P))

2.5 µg/mL

酶联免疫吸附实验 (ELISA)

1:10,000-1:20,000

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Anti-MD-1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide from near the internal region of human MD-1.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.2

内含物

0.02% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

MD-1, also known as LY86, is a glycoprotein involved in innate immunity. It is a component of the RP105/MD-1 complex, which is expressed primarily in immune cells like B-cells. MD-1 is structurally similar to MD-2, sharing only 16% sequence identity, yet both are implicated in lipopolysaccharide recognition. The protein contains the ML (MD-2-related lipid-recognition) domain, which is conserved across various species and mediates diverse biological functions by interacting with specific lipids. Structurally, MD-1 is characterized by a beta-rich fold consisting of multiple strands, which is integral to its biological activities. Though MD-1 mainly associates with RP105, its role in lipid recognition suggests functional similarities with proteins such as GM2A and NPC2, implying participation in broader immune signaling pathways.

仅用于科研。不用于诊断过程。未经明确授权不得转售。