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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
This antibody detects endogenous protein at a molecular weight of 25 kDa.
Purity is >95% by SDS-PAGE.
MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MyoD family inhibitor; Myogenic repressor I-mf
基因别名: I-mf; I-mfa; Mdfi; RGD1560271
UniProt ID: (Mouse) P70331
Entrez Gene ID: (Mouse) 17240, (Rat) 501097