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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Positive Samples: U-251MG, HT-29, MCF7, Mouse brain, Mouse liver, Rat brain; Cellular Location: Basolateral cell membrane, Cell membrane, Cell projection, Single-pass type I membrane protein, phagocytic cup
Immunogen sequence: ADYTISGTLP HSNGGNANSH YFTNPSYHTL TQCATSPHVN NRDRMTVTKS KNNQLFVNLK NVNPGKRGPV GDCTGTLPAD WKHGGYLNEL GAFGLDRSYM GKSLKDLGKN SEYNSSNCSL SSSENPYATI KDPPV
This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Multiple EGF-like domains protein 10; Multiple epidermal growth factor-like domains protein 10
基因别名: 3000002B06Rik; Gm331; Megf10
UniProt ID: (Mouse) Q6DIB5
Entrez Gene ID: (Mouse) 70417, (Rat) 291445