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Antibodies Inc
MESD Monoclonal Antibody (N88/12), FL490
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产品信息
75-129-FL490
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
N88/12
抗原
Fusion protein amino acids 30-95 and 118-180 (lacking VSD domain) of mouse MESD (accession number Q9ERE7) produced recombinantly in E. Coli.
偶联物
激发/发射光谱
491/515 nm
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
靶标信息
MESDC2 chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4. May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: LDLR chaperone MESD; LRP chaperone MESD; mesoderm development candiate 2; Mesoderm development candidate 2; Mesoderm development LRP chaperone MESD; Mesoderm development protein; Renal carcinoma antigen NY-REN-61
基因别名: 2210015O11Rik; AW537813; BOCA; KIAA0081; MESD; MESDC2; MESDM; mKIAA0081; msd; UNQ1911/PRO4369
UniProt ID: (Human) Q14696, (Mouse) Q9ERE7, (Rat) Q5U2R7
Entrez Gene ID: (Human) 23184, (Mouse) 67943, (Rat) 308796
