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Invitrogen
MMP27 Polyclonal Antibody
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产品信息
PA5-49724
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region derived from 440-452 amino acids of Human matrix metallopeptidase 27
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects endogenous level of total MMP27 protein.
靶标信息
Metalloproteinases (MMPs) are a family of proteins that are involved in the breakdown of the extracellular matrix during normal cellular events, including reproduction, tissue remodeling and embryonic development. MMPs are crucial in tumor invasion and building of metastatic formations because of their ability to degrade extracellular matrix proteins such as fibronectin, laminin, gelatins and/or collagen. MMP-27 (matrix metallopeptidase 27) is a 513 amino acid secreted protein that is expressed in B-cells. Belonging to the peptidase M10A family, MMP-27 contains four hemopexin-like domains, which is suggested to be involved in substrate recognition. MMP-27, along with other MMP family members, is associated with breast cancer development and tumor progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: matrix metallo protease; matrix metalloprotease 27; matrix metalloproteinase 27; Matrix metalloproteinase-27; MMP; MMP-27; MMPs
基因别名: Gm180; MMP-27; MMP27; UNQ2503/PRO5992
UniProt ID: (Human) Q9H306
Entrez Gene ID: (Human) 64066, (Mouse) 234911
