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Invitrogen
MRCK beta Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-99655
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CDC42BPB(Accession Q9Y5S2), corresponding to amino acid residues G1645-H1695.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total MRCKbeta.
靶标信息
CDC42BPB is a serine/threonine kinases which functions in actin cytoskeleton assembly and organization. Myotonic dystrophy kinaserelated Cdc42-binding (DMPK-like) kinases-alpha and beta (MRCK-alpha, beta) contain a cysteine-rich motif and a putative pleckstrin homology domain. MRCKs can phosphorylate nonmuscle Myosin light chain and influences Actin-Myosin contractility. MRCK-alpha can phosphorylate and activate LIM kinases downstream of Cdc42, which leads to inactivation of ADF/Cofilin and to Actin cytoskeletal reorganization. MRCK-alpha can also influence neurite outgrowth promoted by Cdc42 and Rac.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CDC42 binding protein kinase beta (DMPK-like); CDC42-binding protein kinase beta; CDC42BP-beta; CDC42BPB; DMPK-like beta; MRCK beta; Myotonic dystrophy kinase-related CDC42-binding kinase beta; myotonic dystrophy protein kinase-like beta; Serine/threonine-protein kinase MRCK beta; unnamed protein product
基因别名: CDC42BPB; CHOCNS; KIAA1124; MRCKB
Entrez Gene ID: (Human) 9578
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