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Invitrogen
MRPL40 Polyclonal Antibody
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Product Details
PA5-52265
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MRPL40. Recombinant protein control fragment (Product #RP-91336).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TQLRETQELI PIEDFITPLK FLDKARERPQ VELTFEETER RALLLKKWSL YKQQERKMER DTIRAMLEAQ QEALEELQLE SPKLHAEAIK RDPNLFPFEK EGPHYTPPIP NYQPPEGRYN DITK
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 77%.
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 39S ribosomal protein L40, mitochondrial; L40mt; Large ribosomal subunit protein mL40; MRP-L40; nuclear localization signal protein absent in velo-cardio-facial patients; Nuclear localization signal-containing protein deleted in velocardiofacial syndrome; Nuclear localization signal-containing protein deleted in velocardiofacial syndrome homolog; Up-regulated in metastasis
Gene Aliases: L40mt; MRP-L22; MRP-L40; MRPL22; MRPL40; NLVCF; URIM
UniProt ID: (Human) Q9NQ50, (Rat) P83565, (Mouse) Q9Z2Q5
Entrez Gene ID: (Human) 64976, (Rat) 287962, (Mouse) 18100
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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