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Invitrogen
MRPL45 Polyclonal Antibody
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产品信息
PA5-89069
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 57-306 of human MRPL45 (NP_1157275)
偶联物
形式
Liquid
浓度
0.74 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MQHARKAGLV IPPEKSDRSI HLACTAGIFD AYVPPEGDAR ISSLSKEGLI ERTERMKKTM ASQVSIRRIK DYDANFKIKD FPEKAKDIFI EAHLCLNNSD HDRLHTLVTE HCFPDMTWDI KYKTVRWSFV ESLEPSHVVQ VRCSSMMNQG NVYGQITVRM HTRQTLAIYD RFGRLMYGQE DVPKDVLEYV VFEKQLTNPY GSWRMHTKIV PPWAPPKQPI LKTVMIPGPQ LKPEEEYEEA QGEAQKPQLA; Positive Samples: U-87MG, OVCAR3, 293T, Mouse brain, Mouse heart, Mouse kidney, Mouse liver, Mouse spleen, Rat brain; Cellular Location: Mitochondrion
靶标信息
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 39S ribosomal protein L45, mitochondrial; L45mt; Large ribosomal subunit protein mL45; MGC11321; MRP-L45
基因别名: 2600005P05Rik; AU043542; L45mt; MRP-L45; Mrpl45; R75241
UniProt ID: (Mouse) Q9D0Q7
Entrez Gene ID: (Human) 84311, (Rat) 287656, (Mouse) 67036
