Search Thermo Fisher Scientific
图: 1 / 4
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene is immediately adjacent to the gene for BAF complex 53 kDa subunit protein a (BAF53a), in a tail-to-tail orientation. Two transcript variants encoding different protein isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 39S ribosomal protein L47, mitochondrial; L47mt; Large ribosomal subunit protein uL29m; nasopharyngeal carcinoma metastasis-related 1; Nasopharyngeal carcinoma metastasis-related protein 1
基因别名: CGI-204; L47mt; MRP-L47; MRPL47; NCM1
UniProt ID: (Human) Q9HD33
Entrez Gene ID: (Human) 57129
分子生物学功能: ribosomal protein