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Invitrogen
MRPS31 Polyclonal Antibody
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产品信息
PA5-109985
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 66-395 of human MRPS31 (NP_005821.2).
偶联物
形式
Liquid
浓度
0.60 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: ICSKKDKQSV RTEETSKETS ESQDSEKENT KKDLLGIIKG MKVELSTVNV RTTKPPKRRP LKSLEATLGR LRRATEYAPK KRIEPLSPEL VAAASAVADS LPFDKQTTKS ELLSQLQQHE EESRAQRDAK RPKISFSNII SDMKVARSAT ARVRSRPELR IQFDEGYDNY PGQEKTDDLK KRKNIFTGKR LNIFDMMAVT KEAPETDTSP SLWDVEFAKQ LATVNEQPLQ NGFEELIQWT KEGKLWEFPI NNEAGFDDDG SEFHEHIFLE KHLESFPKQG PIRHFMELVT CGLSKNPYLS VKQKVEHIEW FRNYFNEKKD ILKESNIQFN
靶标信息
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes; however, its relationship to the etiology of this disease remains to be clarified. Pseudogenes corresponding to this gene have been found on chromosomes 3 and 13.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 28S ribosomal protein S31, mitochondrial; Imogen 38; MRP-S31; Small ribosomal subunit protein mS31
基因别名: IMOGN38; MRP-S31; MRPS31; S31mt
UniProt ID: (Human) Q92665, (Rat) B0BN56
Entrez Gene ID: (Human) 10240, (Rat) 290850
