Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
NeoBiotechnologies
MSH2 (DNA Mismatch Repair Marker) Recombinant Mouse Monoclonal Antibody (MSVA-902M)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 1
MSH2 (DNA Mismatch Repair Marker) Antibody (4436-MSM85-P1) in IHC (P)
DNA mismatch repair protein Msh2 Mouse Recombinant Monoclonal Antibody (MSVA-902M) tested on many normal and cancer tissues. The immunohistochemistry staining in these tissues aligns with the expression data in Human Protein Atlas.
产品信息
4436-MSM85-P1
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
MSVA-902M
抗原
Recombinant full-length human MSH2 protein.
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
Protein A
保存液
PBS with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product cellular localization: Lysosome.
Positive control: Spleen: Numerous granulocytes with strong MPO staining should be seen within the red pulp of the spleen.
靶标信息
Plays a role in neurogenesis and neuronal migration. Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: DNA mismatch repair protein Msh2; hMSH2; Msh2p; mutS homolog 2, colon cancer, nonpolyposis type 1; MutS protein homolog 2
基因别名: COCA1; FCC1; HNPCC; HNPCC1; LCFS2; MSH2
UniProt ID: (Human) P43246
Entrez Gene ID: (Human) 4436
magnesium ion binding
four-way junction DNA binding
Y-form DNA binding
heteroduplex DNA loop binding
double-strand/single-strand DNA junction binding
DNA binding
double-stranded DNA binding
single-stranded DNA binding
protein binding
ATP binding
protein C-terminus binding
ATPase activity
centromeric DNA binding
enzyme binding
protein kinase binding
mismatched DNA binding
guanine/thymine mispair binding
dinucleotide insertion or deletion binding
single guanine insertion binding
single thymine insertion binding
dinucleotide repeat insertion binding
oxidized purine DNA binding
MutLalpha complex binding
protein homodimerization activity
ADP binding
DNA metabolism protein
meiotic mismatch repair
in utero embryonic development
oxidative phosphorylation
DNA repair
mismatch repair
postreplication repair
double-strand break repair
meiotic gene conversion
cell cycle arrest
reciprocal meiotic recombination
germ cell development
determination of adult lifespan
male gonad development
response to X-ray
response to UV-B
somatic hypermutation of immunoglobulin genes
somatic recombination of immunoglobulin gene segments
B cell mediated immunity
B cell differentiation
intra-S DNA damage checkpoint
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of neuron apoptotic process
maintenance of DNA repeat elements
negative regulation of reciprocal meiotic recombination
isotype switching
negative regulation of DNA recombination
positive regulation of helicase activity
