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Proteintech
MSI2 Polyclonal Antibody
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Product Details
10770-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MSI2 Fusion Protein Ag1213 (1-328 aa encoded by BC001526)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MEANGSQGT SGSANDSQHD PGKMFIGGLS WQTSPDSLRD YFSKFGEIRE CMVMRDPTTK RSRGFGFVTF ADPASVDKVL GQPHHELDSK TIDPKVAFPR RAQPKMVTRT KKIFVGGLSA NTVVEDVKQY FEQFGKVEDA MLMFDKTTNR HRGFGFVTFE NEDVVEKVCE IHFHEINNKM VECKKAQPKE VMFPPGTRGR ARGLPYTMDA FMLGMGMLGY PNFVATYGRG YPGFAPSYGY QFPGFPAAAY GPVAAAAVAA ARGSGSNPAR PGGFPGANSP GPVADLYGPA SQDSGVGNYI SAASPQPGSG FGHGIAGPLI ATAFTNGYH (1-328 aa encoded by BC001526 )
Target Information
Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.Tissue specificity: Ubiquitous; detected at low levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Musashi homolog 2; musashi RNA-binding protein 2; Musashi-2; Musashi2; RNA-binding protein Musashi homolog 2
Gene Aliases: 1700105C15Rik; AI451722; AI563628; AW489193; MSI2; MSI2H; RGD1560397
UniProt ID: (Human) Q96DH6, (Mouse) Q920Q6
Entrez Gene ID: (Human) 124540, (Mouse) 76626, (Rat) 360596
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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