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Invitrogen
MTTP Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-102474
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human MTTP(Accession P55157), corresponding to amino acid residues G655-T705.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total MTTP.
靶标信息
MTTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a entral role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC149819; MGC149820; microsomal triglyceride transfer protein (large polypeptide, 88kDa); microsomal triglyceride transfer protein B; microsomal triglyceride transfer protein, large subunit; MTP-B; unnamed protein product
基因别名: 1810043K16Rik; ABL; MTP
UniProt ID: (Human) P55157, (Rat) D4A1W8, (Mouse) O08601
Entrez Gene ID: (Human) 4547, (Rat) 310900, (Mouse) 17777
lipid transporter activity
protein binding
lipid binding
apolipoprotein binding
macromolecular complex binding
protein heterodimerization activity
intermembrane phospholipid transfer activity
phosphatidylcholine transfer activity
intermembrane cholesterol transfer activity
triglyceride transfer activity
ceramide 1-phosphate transporter activity
phosphatidylethanolamine transporter activity
lipid metabolic process
lipid transport
circadian rhythm
protein secretion
phospholipid transport
sterol transport
triglyceride transport
plasma lipoprotein particle assembly
chylomicron assembly
very-low-density lipoprotein particle assembly
lipoprotein metabolic process
cholesterol homeostasis
response to calcium ion
intermembrane lipid transfer
ceramide 1-phosphate transport
glycolytic process
protein lipidation
glutamine metabolic process
triglyceride metabolic process
cholesterol metabolic process
gene expression
low-density lipoprotein particle remodeling
very-low-density lipoprotein particle clearance
lipoprotein transport
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
