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Invitrogen
MXD1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-51609
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
20 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LCLEKLKGLV PLGPESSRHT TLSLLTKAKL HIKKLEDCDR KAVHQIDQLQ REQRHLKRQL EKLGIERIRM DSIGSTVSSE RSDSDREEID VDVESTDYLT GDLDWSSSSV SDSDERGSMQ SLGSDEGYSS TSI
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 84%.
靶标信息
MAX dimerization protein belongs to a subfamily of MAX-interacting proteins. This protein competes with MYC for binding to MAX to form a sequence-specific DNA-binding complex, acts as a transcriptional repressor (while MYC appears to function as an activator) and is a candidate tumor suppressor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: antagonizer of myc transcriptional activity; MAD; max dimerizer 1; MAX-binding protein; MGC104659; OTTHUMP00000202211; unnamed protein product
基因别名: BHLHC58; MAD; MAD1
UniProt ID: (Human) Q05195
Entrez Gene ID: (Human) 4084
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
protein binding
protein dimerization activity
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