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Abnova
MYST1 Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 1
MYST1 Antibody (H00084148-D01P) in WB
Western Blot analysis of MYST1 expression in transfected 293T cell line (H00084148-T01) by MYST1 MaxPab polyclonal antibody.
Lane 1: MYST1 transfected lysate(53.10 KDa).
Lane 2: Non-transfected lysate.
Lane 1: MYST1 transfected lysate(53.10 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00084148-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MYST1 (AAH37773.1, 1 a.a. approximately 467 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MAAQGAAAAV AAGTSGVAGE GEPGPGENAA AEGTAPSPGR VSPPTPARGE PEVTVEIGET YLCRRPDSTW HSAEVIQSRV NDQEGREEFY VHYVGFNRRL DEWVDKNRLA LTKTVKDAVQ KNSEKYLSEL AEQPERKITR NQKRKHDEIN HVQKTYAEMD PTTAALEKEH EAITKVKYVD KIHIGNYEID AWYFSPFPED YGKQPKLWLC EYCLKYMKYE KSYRFHLGQC QWRQPPGKEI YRKSNISVYE VDGKDHKIYC QNLCLLAKLF LDHKTLYFDV EPFVFYILTE VDRQGAHIVG YFSKEKESPD GNNVACILTL PPYQRRGYGK FLIAFSYELS KLESTVGSPE KPLSDLGKLS YRSYWSWVLL EILRDFRGTL SIKDLSQMTS ITQNDIISTL QSLNMVKYWK GQHVICVTPK LVEEHLKSAQ YKKPPITGGW GAAVCRGRWG SVSMWTGRSQ GLLIAVT
Target Information
The MYST family of histone acetyltransferases, which includes MYST1, is named for the founding members MOZ (MYST3), yeast YBF2 and SAS2, and TIP60 (HTATIP). All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein-protein interactions and targeting transcriptional regulators to chromatin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: h FLJ14040; Histone acetyltransferase KAT8; histone acetyltransferase MYST1; hMOF; K(lysine) acetyltransferase 8; Lysine acetyltransferase 8; Males-absent on the first protein homolog; MOF; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; MYST family member; MYST histone acetyltransferase 1; MYST-1; ortholog of Drosophila males absent on the first (MOF); probable histone acetyltransferase MYST1; Protein acetyltransferase KAT8; Protein propionyltransferase KAT8; unnamed protein product
Gene Aliases: hMOF; KAT8; LIGOWS; MOF; MYST1; PP7073; ZC2HC8
UniProt ID: (Human) Q9H7Z6
Entrez Gene ID: (Human) 84148
transcription coactivator activity
histone acetyltransferase activity
protein binding
zinc ion binding
H4 histone acetyltransferase activity
acetyltransferase activity
transferase activity
transferase activity, transferring acyl groups
enzyme binding
histone acetyltransferase activity (H4-K5 specific)
histone acetyltransferase activity (H4-K8 specific)
metal ion binding
histone acetyltransferase activity (H4-K16 specific)
RNA polymerase II sequence-specific DNA binding transcription factor binding
peptide-lysine-N-acetyltransferase activity
protein propionyltransferase activity
DNA-binding transcription factor binding
promoter-specific chromatin binding
epithelial to mesenchymal transition
chromatin organization
regulation of transcription, DNA-templated
dosage compensation by inactivation of X chromosome
regulation of autophagy
negative regulation of macromolecule biosynthetic process
positive regulation of epithelial to mesenchymal transition
negative regulation of epithelial to mesenchymal transition
skeletal muscle satellite cell differentiation
neurogenesis
hemopoiesis
myeloid cell differentiation
negative regulation of type I interferon production
positive regulation of type I interferon production
post-embryonic hemopoiesis
regulation of gene expression, epigenetic
regulation of cell differentiation
positive regulation of gene expression, epigenetic
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
oogenesis
regulation of mRNA processing
negative regulation of multicellular organismal process
positive regulation of transcription initiation from RNA polymerase II promoter
membraneless organelle assembly
positive regulation of skeletal muscle satellite cell differentiation
regulation of transcription from mitochondrial promoter
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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