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          • Primary Antibodies ›
          • Myeloperoxidase Antibodies

          Invitrogen

          Myeloperoxidase Monoclonal Antibody (MPO421-8B2), PE-Cyanine7

          View all (63) Myeloperoxidase antibodies

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          Cite Myeloperoxidase Monoclonal Antibody (MPO421-8B2), PE-Cyanine7

          Additional Information:

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          • Antibody Testing Data (2)
          Myeloperoxidase Antibody in Flow Cytometry (Flow)
          Group 53 Created with Sketch.
          Myeloperoxidase Antibody in Flow Cytometry (Flow)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          Myeloperoxidase Antibody (MA574423) in Flow

          Flow cytometry analysis of Myeloperoxidase in human neutrophil granulocytes (red-filled); lymphocytes (black-dashed). Samples were incubated with monoclonal Myeloperoxidase (Product # MA574423) at a dilution of 1.67 μg/mL, followed by PE-Cy 7. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          Myeloperoxidase Antibody in Flow Cytometry (Flow)
          Myeloperoxidase Antibody in Flow Cytometry (Flow)

          Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

          Myeloperoxidase Monoclonal Antibody (MPO421-8B2), PE-Cyanine7

          Product Details

          MA574423

          Applications
          Tested Dilution
          Publications

          Flow Cytometry (Flow)

          4 µL/10^6 cells
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Mouse / IgG1

          Class

          Monoclonal

          Type

          Antibody

          Clone

          MPO421-8B2

          Immunogen

          Human myeloperoxidase.
          3D Epitope / Immunogen

          Conjugate

          PE-Cyanine7 PE-Cyanine7 PE-Cyanine7
          • Unconjugated
          • Alexa Fluor 647 
          • PE 
          • Request custom conjugation

          Excitation/Emission Max

          569/780 nm View spectra spectra

          Form

          Liquid

          Purification

          Size-exclusion chromatography

          Storage buffer

          PBS, pH 7.4, with 0.2% BSA

          Contains

          15mM sodium azide

          Storage conditions

          4°C, store in dark, DO NOT FREEZE!

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer's Disease, Familial, 1.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          How to use the Panel Builder

          Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: unnamed protein product

          View more View less

          UniProt ID: (Human) P05164

          View more View less

          Entrez Gene ID: (Human) 4353

          View more View less

          Function(s)
          chromatin binding peroxidase activity protein binding heparin binding heme binding nucleosome binding thiocyanate peroxidase activity protein-containing complex destabilizing activity
          Process(es)
          nucleosome disassembly defense response response to oxidative stress response to mechanical stimulus thiocyanate metabolic process response to food response to lipopolysaccharide low-density lipoprotein particle remodeling defense response to bacterium hydrogen peroxide catabolic process negative regulation of apoptotic process neutrophil-mediated killing of symbiont cell neutrophil mediated killing of bacterium neutrophil mediated killing of fungus cellular oxidant detoxification neutrophil extracellular trap formation positive regulation of cholesterol import response to gold nanoparticle
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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