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Abnova
N-PAC Polyclonal Antibody, MaxPab™
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产品信息
H00084656-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
N-PAC (AAH64940.1, 1 a.a. approximately 484 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MIKINKGKRF QQAVDAVEEF LRRAKGKDQT SSHNSSDDKN RRNSSEERSR PNSGDEKRKL SLSEGKVKKN MGEGKKRVSS GSSERGSKSP LKRAQEQSPR KRGRPPKDEK DLTIPESSTV KGMMAGPMAA FKWQPTASEP VKDADPHFHH FLLSQTEKPA VCYQAITKKL KICEEETGST SIQAADSTAV NGSITPTDKK IGFLGLGLMG SGIVSNLLKM GHTVTVWNRT AEKCDLFIQE GARLGRTPAE VVSTCDITFA CVSDPKAAKD LVLGPSGVLQ GIRPGKCYVD MSTVDADTVT ELAQVIVSRG GRFLEAPVSG NQQLSNDGML VILAAGDRGL YEDCSSCFQA MGKTSFFLGE VGNAAKMMLI VNMVQGSFMA TIAEGLTLAQ VTGQSQQTLL DILNQGQLAS IFLDQKCQNI LQGNFKPDFY LKYIQKDLRL AIALGDAVNH PTPMAAAANE VYKRAKALDQ SDNDMSAVYR AYIH
靶标信息
GLYR1 may have oxidoreductase activity. It regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. It indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6. It is recruited on chromatin, recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3-hydroxyisobutyrate dehydrogenase-like protein; Cytokine-like nuclear factor N-PAC; Glyoxylate reductase 1 homolog; hNDF; NPAC; nuclear protein 60 kDa; nuclear protein 60kDa; Nuclear protein NP60; Nuclear protein of 60 kDa; Nucleosome-destabilizing factor; Putative oxidoreductase GLYR1
基因别名: BM045; GLYR1; HIBDL; N-PAC; NDF; NP60; NPAC
UniProt ID: (Human) Q49A26
Entrez Gene ID: (Human) 84656
