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Invitrogen
NEK6 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-67942
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human NEK6.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
NEK6 kinase is a member of the NEK family. NEK6 is a serine/threonine kinase that controls the initiation of mitosis and is required for the metaphase-anaphase transition. The Aspergillus nidulans 'never in mitosis A' (NIMA) gene encodes a serine/threonine kinase that controls initiation of mitosis. NIMA-related kinases (NEKs) are a group of protein kinases that are homologous to NIMA. Evidence suggests that NEKs perform functions similar to those of NIMA. NEK6 encodes a NEK type protein kinase, which contains a C-terminal NIMA-like catalytic domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Never in mitosis A-related kinase 6; NIMA (never in mitosis gene a)-related expressed kinase 6; NIMA-related expressed kinase 6; NimA-related protein kinase 6; Protein kinase SID6-1512; RP11-101K10.6; Serine/threonine-protein kinase Nek6; SID
Gene Aliases: 1300007C09Rik; NEK6
UniProt ID: (Mouse) Q9ES70, (Rat) P59895
Entrez Gene ID: (Mouse) 59126, (Rat) 360161
nucleotide binding
magnesium ion binding
protein kinase activity
protein serine/threonine kinase activity
signal transducer activity
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinesin binding
protein kinase binding
metal ion binding
non-receptor serine/threonine protein kinase
protein phosphorylation
apoptotic process
cell cycle
chromosome segregation
mitotic nuclear division
signal transduction
regulation of signal transduction
phosphorylation
peptidyl-serine phosphorylation
regulation of mitotic metaphase/anaphase transition
G2 DNA damage checkpoint
positive regulation of I-kappaB kinase/NF-kappaB signaling
protein autophosphorylation
cell division
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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