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Invitrogen
NGAL Polyclonal Antibody
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NGAL Antibody (PA5-79590) in IHC (P)
Immunohistochemistry analysis of NGAL on paraffin-embedded mouse spleen tissue. Antigen retrieval was performed using citrate buffer (pH6, epitope retrieval solution) for 20 mins. Sample was blocked using 10% goat serum, incubated with NGAL polyclonal antibody (Product# PA5-79590) with a dilution of 1 µg/mL (overnight at 4°C), and followed by biotinylated goat anti-rabbit IgG (30 minutes at 37°C). Developme... View More
产品信息
PA5-79590
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
已发表种属
C. elegans,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived mouse Lipocalin 2 recombinant protein (Position: Q21-N200).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: mouse spleen tissue. IHC: Mouse Spleen tissue, Rat Spleen tissue IHC-F: mouse lung tissue, mouse spleen tissue, rat lung tissue, rat spleen tissue.
靶标信息
NGAL (Neutrophil gelatinase-associated lipocalin, lipocalin 2, siderocalin and neutrophil lipocalin) is a 25 kDa glycosylated single chain monomer and member of the lipocalin family of proteins that bind and transport small lipophilic molecules. NGAL is released by activated neutrophils, can form dimers and small amounts of higher oligomers, and complexes with matrix metalloproteinase 9 (MMP-9, gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by ischemic or nephrotoxic kidney injury.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 24p3; Alpha-2-microglobulin-related protein; Alpha-2U globulin-related protein; HGNC:6526; lipocalin 2 (oncogene 24p3); Lipocalin 24p3; Lipocalin-2; Lipocalin2; Neutrophil gelatinase-associated lipocalin; NGAL; Oncogene 24p3; OTTHUMP00000022240; p25; RP23-161B9.11; secreted inducible protein 24; Siderocalin LCN2; SV-40-induced 24P3 protein; uterocalin
基因别名: 24p3; AW212229; Lcn2; Sip24
UniProt ID: (Mouse) P11672, (Rat) P30152
Entrez Gene ID: (Mouse) 16819, (Rat) 170496
immune system process
transport
ion transport
apoptotic process
response to virus
response to herbicide
positive regulation of gene expression
siderophore transport
positive regulation of cell projection organization
response to drug
innate immune response
iron ion homeostasis
protein homotrimerization
cellular response to hydrogen peroxide
extrinsic apoptotic signaling pathway in absence of ligand
response to oxidative stress
response to bacterium
response to mycotoxin
response to nutrient levels
cellular response to nutrient levels
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to tumor necrosis factor
