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Invitrogen
NOC2L Polyclonal Antibody
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产品信息
PA1-41264
产品规格
种属反应
Bovine,
Human,
Non-human primate
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptides of amino acids 87-103 and 231-246 of human INHAT-2.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein G
保存液
PBS with 100µg/mL BSA
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Suggested positive control: Hela whole cell extract, HeLa cell lysate.
Reacts with Chimpanzee and Rhesus Monkey. Predicted to react with Chicken, Mouse and Rat.
靶标信息
INHAT (inhibitor of acetyltransferases) complex binds to histones and masks them from being substrate for acetyltransferase. Endogenous INHAT subunits, which include the Set/TAF-Ibeta oncoprotein, associate with chromatin in vivo and can block coactivator mediated transcription when transfected in cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp564C186; FLJ35172; NOC2-like; NOC2-like nucleolar associated transcriptional repressor; NOC2-like protein; NOC2L nucleolar associated transcriptional repressor; novel INHAT (inhibitor of histone acetyltransferase) repressor; Novel INHAT repressor; nucleolar complex associated 2 homolog; Nucleolar complex protein 2 homolog; Protein NOC2 homolog; protein phosphatase 1, regulatory subunit 12
基因别名: NET15; NET7; NIR; NOC2L; PPP1R112
UniProt ID: (Human) Q9Y3T9, (Bovine) Q3SYU1
Entrez Gene ID: (Human) 26155, (Bovine) 508638
negative regulation of transcription from RNA polymerase II promoter
negative regulation of B cell apoptotic process
transcription, DNA-templated
apoptotic process
chromatin assembly
nucleolus to nucleoplasm transport
cellular response to UV
negative regulation of histone acetylation
ribosomal large subunit biogenesis
regulation of signal transduction by p53 class mediator
negative regulation of intrinsic apoptotic signaling pathway
