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Immunogen sequence: YALAGVSFEI KAEDDQPLPG VLLSLSGGLF RSNLLTQDNG ILTFSNLSPG QYYFKPMMKE FRFEPSSQMI EVQEGQNLKI TITGYRTAYS CYGTVSSLNG EPEQGVAMEA VGQNDCSIYG EDTVTDEEGK FRLRGLLPGC VYHVQLKAEG NDHIERALPH HRVIEVGNND IDDVNIIVFR QINQFDLSGN VITSSEYLPT LWVKLYKSEN LDNPIQTVSL GQSLFFHFPP LLRDGENYVV LLDSTLPRSQ YDYILPQVSF TAVGYHKHIT LIFNPTRKLP EQDIAQGSYI ALPLTLLVLL AGYNHDKLIP LLLQLTSRLQ GVGALGQAAS DNSGPEDAKR QAKKQKTRRT; Positive Samples: BxPC3; Cellular Location: Endoplasmic reticulum membrane, Single-pass membrane protein
This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE). Two transcripts encoding different isoforms have been described.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BOS complex subunit NOMO2; Nodal modulator 2; pM5 protein 2; pM5 protein, centromeric copy
基因别名: Nomo; NOMO2; PM5
UniProt ID: (Human) Q5JPE7
Entrez Gene ID: (Human) 283820