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Invitrogen
NPHP3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-113061
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Nephrocystin-3 protein (1-130AA)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.52 mg/mL
规格
52 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Nephrocystin-3
基因别名: 3632410F03Rik; AI550417; C230078J01; D330020E01Rik; KIAA2000; NPHP3; pcy
UniProt ID: (Mouse) Q7TNH6
Entrez Gene ID: (Mouse) 74025
kidney development
heart looping
atrial septum development
lipid metabolic process
establishment or maintenance of cell polarity
determination of left/right symmetry
Wnt signaling pathway
extracellular matrix organization
lung development
regulation of cAMP metabolic process
determination of pancreatic left/right asymmetry
photoreceptor cell maintenance
maintenance of organ identity
convergent extension involved in gastrulation
cilium morphogenesis
kidney morphogenesis
determination of intestine left/right asymmetry
determination of stomach left/right asymmetry
determination of liver left/right asymmetry
ureter development
negative regulation of canonical Wnt signaling pathway
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