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Invitrogen
Oncomodulin Polyclonal Antibody
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Oncomodulin Antibody (PA5-47832) in WB
Western blot analysis of Oncomodulin in rat placenta tissue. Samples were incubated in Oncomodulin polyclonal antibody (Product # PA5-47832) using a dilution of 1 µg/mL followed by a HRP-conjugated Anti-Goat IgG secondary antibody. A specific band was detected for Oncomodulin at approximately 12 kDa (as indicated). This experiment was conducted under reducing conditions.
产品信息
PA5-47832
产品规格
种属反应
Rat
已发表种属
C. elegans
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived recombinant rat Oncomodulin Met1-Ser109
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In direct ELISAs, approximately 40% cross-reactivity with recombinant human Oncomodulin is observed.
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
靶标信息
Oncomodulin, encoded by the OCM gene located on chromosome 7p22.3, is a protein that belongs to the parvalbumin family of calcium-binding proteins. It is most prominently found in the inner ear, as well as in certain retinal cells and regenerating neurons. Oncomodulin plays a crucial role in calcium ion homeostasis, which is vital for various cellular processes, including signal transduction, cellular motility, and growth. Notably, oncomodulin has been studied for its role in promoting nerve regeneration, particularly within the central nervous system, where it enhances axonal growth and neuronal repair. This makes it a molecule of significant interest for therapeutic strategies aiming to treat nerve injuries or neurodegenerative diseases. Beyond its neuroregenerative potential, oncomodulin is also expressed in some tumor types, which initially led to its association with cancer-related studies. Current research continues to explore its dual roles in both oncology and neurobiology to better understand its functional implications across different tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: OM; Oncomodulin; Parvalbumin beta
基因别名: Ocm; OM; oncmodulin
UniProt ID: (Rat) P02631
Entrez Gene ID: (Rat) 25503
