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Invitrogen
P2X5 Polyclonal Antibody
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Product Details
PA5-79778
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human P2X5 recombinant protein (Position: D333-T422).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 0.9mg NaCl, 0.2mg Na2PO4, 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Brain Tissue. IHC: Mouse Brain Tissue, Rat Brain Tissue.
Target Information
The P2X5 gene encodes a protein that is a member of the purinergic receptor family, P2X receptors. These receptors are ligand-gated ion channels activated by extracellular ATP. The P2X5 protein is primarily involved in the regulation of skeletal muscle, immune response, and sensory neuron functions. Structurally, P2X5 features two transmembrane domains, a large extracellular loop, and intracellular N- and C-termini. P2X5 is known to form both homomeric and heteromeric channels, contributing to its functional diversity in various tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP receptor; ATP receptor subunit; ionotropic ATP receptor P2X5; lymphoid-restricted histocompatibility antigen-1; Membrane magnesium transporter 2; membrane magnesium transporter 2 {ECO:0000250|UniProtKB:Q8R3L0}; MGC47755; mmgt2; mmgt2 {ECO:0000250|UniProtKB:Q8R3L0}; P2RX5; P2X purinoceptor 5; P2X5; Purinergic receptor; purinergic receptor P2X, ligand gated ion channel, 5; purinergic receptor P2X5-2; unnamed protein product
Gene Aliases: AI852046; LRH-1; Mmgt2; P2RX5; P2X5; P2X5FL; P2X5R; RGD1311260
UniProt ID: (Rat) Q6P719, (Mouse) Q8R3L0, (Human) Q93086, (Mouse) Q91VE2, (Rat) P51578
Entrez Gene ID: (Rat) 303211, (Mouse) 216829, (Human) 5026, (Mouse) 94045, (Rat) 113995
magnesium ion transmembrane transporter activity
copper ion transmembrane transporter activity
manganese ion transmembrane transporter activity
cobalt ion transmembrane transporter activity
nickel cation transmembrane transporter activity
inorganic cation transmembrane transporter activity
purinergic nucleotide receptor activity
transmembrane signaling receptor activity
extracellular ATP-gated cation channel activity
ion channel activity
voltage-gated ion channel activity
ATP binding
channel activity
ATP-gated ion channel activity
identical protein binding
ligand-gated monoatomic anion channel activity
GTP binding
drug binding
zinc ion binding
ligand-gated ion channel
magnesium ion transport
transport
cation transport
cobalt ion transport
copper ion transport
manganese ion transport
nickel cation transport
copper ion transmembrane transport
nickel cation transmembrane transport
manganese ion transmembrane transport
ion transport
chloride transport
signal transduction
nervous system development
response to pH
response to zinc ion
positive regulation of calcium ion transport into cytosol
response to ATP
ion transmembrane transport
purinergic nucleotide receptor signaling pathway
osteoclast maturation
regulation of skeletal muscle tissue regeneration
positive regulation of calcium-mediated signaling
response to calcium ion
excitatory postsynaptic potential
calcium ion transmembrane transport
cation transmembrane transport
anion transmembrane transport
positive regulation of calcium ion import across plasma membrane
cell surface receptor signaling pathway
neuronal action potential
protein homooligomerization
mitophagy in response to mitochondrial depolarization
skeletal muscle tissue growth
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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