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Invitrogen
PACAP-38 (Biosimilar) Recombinant Human Monoclonal Antibody
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产品信息
MA5-58905
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG1
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
偶联物
形式
Lyophilized
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
25mM histidine, pH 6.2, with 8% sucrose, 0.01% Tween 80
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Dry ice (international)
RRID
产品详细信息
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
This antibody can also be cross referenced by the term Lilly patent anti-PACAP.
靶标信息
Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adenylate cyclase activating polypeptide 1 (pituitary); PACAP; Pituitary adenylate cyclase-activating polypeptide; prepro-PACAP; unnamed protein product
基因别名: ADCYAP1; PACAP
UniProt ID: (Human) P18509
Entrez Gene ID: (Human) 116
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
cell-cell signaling
nervous system development
female pregnancy
regulation of G-protein coupled receptor protein signaling pathway
positive regulation of gene expression
insulin secretion
neuron projection development
regulation of protein localization
positive regulation of GTPase activity
negative regulation of cell cycle
positive regulation of protein kinase activity
positive regulation of transcription from RNA polymerase II promoter
positive regulation of growth hormone secretion
positive regulation of ERK1 and ERK2 cascade
positive regulation of chemokine (C-C motif) ligand 5 production
positive regulation of cold-induced thermogenesis
positive regulation of cAMP/PKA signal transduction
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