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Invitrogen
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This target displays homology in the following species: Cow: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 87%; Yeast: 85%
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 domain and a semi-Cdc42/Rac interactive binding domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: PAR-6; par-6 (partitioning defective 6,) homolog alpha; PAR-6 alpha; Partitioning defective 6 homolog alpha; Tax interaction protein 40
基因别名: 0710008C04Rik; 2610010A15Rik; Par-6; PAR-6A; Par6; Par6a; PAR6alpha; Par6c; Pard6a; TAX40; Tip-40
UniProt ID: (Mouse) Q9Z101
Entrez Gene ID: (Mouse) 56513