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The antibody detects endogenous levels of total PDZD2 protein.
Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signaling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Activated in prostate cancer protein; PDZ domain-containing protein 2; PDZ domain-containing protein 3; plakophilin-related armadillo repeat protein-interactive PDZ protein; Processed PDZ domain-containing protein 2
基因别名: AIPC; KIAA0300; PAPIN; PDZD2; PDZK3; PIN1
UniProt ID: (Human) O15018
Entrez Gene ID: (Human) 23037
分子生物学功能: interleukin superfamily