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Peptide sequence: PSPNQSYQGS SGYNFRPTDA RCLPSSPIRM FASFHPSAST AGTSGDSGPP
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%
This gene encodes a protein with significant sequence similarity to Drosophila Polycomblike. The encoded protein contains a zinc finger-like PHD (plant homeodomain) finger which is distinct from other classes of zinc finger motifs and which shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. Two transcript variants have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hPCl1; PHD finger protein 1; Polycomb-like protein 1; Protein PHF1; testicular tissue protein Li 140; tudor domain containing 19C
基因别名: hPHF1; MTF2L2; PCL1; PHF1; PHF2; TDRD19C
UniProt ID: (Human) O43189
Entrez Gene ID: (Human) 5252
分子生物学功能: chromatin/chromatin-binding, or -regulatory protein