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Recommended positive controls: 293T, mouse testis.
Predicted reactivity: Mouse (91%), Rat (91%), Rhesus Monkey (99%), Bovine (93%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
PIM2 is a proto-oncogene which phosphorylates BAD, which partially inhibits its apopotopic function. PIM proteins (PIM-1, PIM-2 and PIM-3) are oncogene-encoded serine/threonine kinases. PIM-2 is highly homologous to Pim-1 with similar oncogenic functions. PIM-2 is most abundantly expressed in hematopoietic tissues, spleen, thymus, and peripheral blood leukocytes, as well as in testis, small intestine, and colon. PIM2 expression is negatively regulated by growth factor depletion. Increased levels of PIM-2 has also been observed in certain cancers.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: pim-2 oncogene; Pim-2h; proto-oncogene Pim-2 (serine threonine kinase); serine/threonine protein kinase pim-2; Serine/threonine-protein kinase pim-2
基因别名: DXCch3; Pim-2; PIM2
UniProt ID: (Human) Q9P1W9, (Mouse) Q62070
Entrez Gene ID: (Human) 11040, (Mouse) 18715