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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: KPSASAPIPIT CSETPTVSQL VSKPHTPSLD EDGINLEEI
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 100%.
Brn-5 (Brain-5), also known as POU6F1, MPOU or TCFB1, is a widely expressed protein but during embryogenesis is exclusively found in the developing brain and spinal cord. As is characteristic of Brn family members, Brn-5 contains two DNA-binding domains, namely the POU-specific domain and the POU homeodomain, which each contain an HTH (helix-turn-helix) motif. Brn-5 binds to CRH (corticotrophin-releasing hormone) elements with high affinity and is capable of both enhancing Prolactin gene expression and activating Pit-1 expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Brain-5; Brain-specific homeobox/POU domain protein 5; mPOU homeobox protein; POU domain, class 6, transcription factor 1
基因别名: BRN5; MPOU; POU6F1; TCFB1
Entrez Gene ID: (Human) 5463