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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: KLQKTYRMEP AGSQGVWGLD DFQFLPFIWG SSQLIDHPYL EPRHFVDEKA VNENHKDYMF LECILFITEM KTGPFAEHSN QLWNISAVPS WSKVNQGLIR MYKAECLEKF PVIQHFKF
Highest antigen sequence indentity to the following orthologs: Rat - 97%, Mouse - 97%.
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MGC2184; OTTHUMP00000022333; Phosphotyrosyl phosphatase activator; PP2A, subunit B', PR53 isoform; PTPA; Serine/threonine-protein phosphatase 2A activator; Serine/threonine-protein phosphatase 2A regulatory subunit 4; Serine/threonine-protein phosphatase 2A regulatory subunit B'
基因别名: PPP2R4; PTPA
Entrez Gene ID: (Human) 5524