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Invitrogen
PRR7 Polyclonal Antibody
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产品信息
PA5-61266
产品规格
种属反应
Human
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MSKPPCYEEA VLMAEPPPPY SEVLTDTRGL YRKIVTPFLS RRDSAEKQEQ PPPSYKPLFL DRGYTSALHL PSAPRPAPPC PALCLQADRG RRVFPSWTDS ELSSREPLEH GAWRLPVSIP
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
靶标信息
PRR7/TRAP3 (proline-rich 7, transmembrane adaptor protein 3) is a 28 kDa transmembrane adaptor protein ubiquitously expressed at low level (most in brain). Its amino acid sequence is extremely conserved among mammalian and other species. PRR7/TRAP3 contains potential palmitoylation motif and is found in lipid rafts. It is a part of the complex postsynaptic density fraction in neurons and associates with PSD-95, NMDA receptor and probably other proteins. The intracellular domain of PRR7/TRAP3 contains several tyrosines, a proline-rich sequence, and a C-terminal PDZ-binding motif. So far nothing is known about function of this protein. It may be involved in regulation of some receptor signaling and in formation of neurologic and immunologic synapse.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: MGC10772; Proline-rich protein 7; Synaptic proline-rich membrane protein
基因别名: PRR7
UniProt ID: (Human) Q8TB68
Entrez Gene ID: (Human) 80758
